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Tuesday, August 23, 2016

Potential CURE for Melanoma, the Deadliest Skin Cancer May Be On Near Horizon

Anyone who has ever had malignant melanoma (as I have) and takes any interest in the disease which will probably kill them, knows that it isn’t the melanoma on the skin which matters - it is entirely benign EXCEPT that sooner or later it will spread to the brain and other organs (metastasis) and that’s what is eventually fatal.

Treatments for MM are basic, beginning with excising (cutting out) the tumor and, 10 years ago, simply hoping it hadn’t spread yet.

Just 10 to 15 years ago if the tumor had spread that was essentially a death sentence because there was no good chemotherapy.

I was fortunate.

My cousin who was diagnosed at almost the same time, wasn’t.

The Situation Today

Today there are various chemotherapy treatments which save many patients at the high cost of making them very sick for a period.

But a recently announced discovery by Israeli researchers at Tel Aviv University holds the hope of an actual CURE for all malignant melanoma if discovered early enough.

What they found were two substances which stop the metastasis of the cancer by preventing the epidermal tumor from reaching a blood vessel and spreading to other organs.

The newly discovered chemicals don’t actually cure melanoma but do something almost as good by preventing the metastasis which is actually the cancer’s danger.

Transforming melanoma into a nonthreatening illness

“Having discovered the mechanism, the researchers proceeded to look for substances that could intervene and block the process in its earliest stages. They found two such chemicals: one (SB202190) inhibits the delivery of the vesicles from the melanoma tumor to the dermis; and the other (U0126) prevents the morphological changes in the dermis even after the arrival of the vesicles. Both substances were tested successfully in the lab, and may serve as promising candidates for future drugs. In addition, the changes in the dermis, as well as the vesicles themselves, can be used as powerful indicators for early diagnosis of melanoma.
"Our study is an important step on the road to a full remedy for the deadliest skin cancer," said Dr. Levy. "We hope that our findings will help turn melanoma into a nonthreatening, easily curable disease."

This discovery has important implications because, if it proves possible to put this into a drug and the drug isn’t dangerous to humans, it would virtually eliminate the threat of malignant melanoma, very important to survivors because it usually reoccurs.

While waiting for a "cure" patients should probably read what I found about Vitamin D-3 and its potential to extend life of MM patients. It was vital before recent chemotherapy advances and today won't interfere with more modern treatments.

See my pamphlet on the subject which includes citations from medical studies published in Europe.

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