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Tuesday, September 21, 2021

Moderna vaccine much more effective than the other two used in the US

Numbers below show effectiveness against hospitalization.

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Moderna 93% initially and still  92% after 120 days 
from second vaccination. 
Pfizer only 91% at first dropping to 77% after 120 days
J&J single shot VE is 71% at first and drops to 68% at 120 days

VE = vaccine effectiveness



VE for the Moderna vaccine was 93% at 14–120 days (median = 66 days) after receipt of the second vaccine dose and 92% at >120 days (median = 141 days) (p = 1.000). VE for the Pfizer-BioNTech vaccine was 91% at 14–120 days (median = 69 days) after receipt of the second vaccine dose but declined significantly to 77% at >120 days (median = 143 days) (p<0.001).

https://www.cdc.gov/mmwr/volumes/70/wr/mm7038e1.htm


Monday, September 13, 2021

Have COVID? Be dog's best friend by avoiding close contact - dogs can catch COVID from their people and vice versa.

Pet owning people with COVID who are at home would probably wish to have the comfort of patting and even hugging man's best friend, but this is a bad idea for several reasons.

First you can easily infect a pet dog leading to symptoms which will not only concern a responsible pet owner but will also cause extra work in caring for the sick animal.

Second, a zoonotic disease (one which can pass between humans and various animals) is extremely dangerous because it provides yet another and especially novel environment which can easily help develop a more dangerous mutation or, to use the recently popular term "variant."

But COVID has been a major boost for shelter adoptions as people who were in lockdown reached out for comfort and companionship to pets. In fact (see link below) some shelters were actually emptied of adoptive dogs which is wonderful if the people don't just dump their new pets back in shelters when the pandemic ends and they are not forced to stay home.

Some, perhaps many will continue to stay home and even work from home as they have experienced the wonderful freedom from dress codes (most punishing for women) and especially from that dreaded daily commute. I know of no one who ever looked forward to spending hours each week sitting in traffic jams.

A pre-print paper cites case studies of pets which developed respiratory symptoms after being in close contact with COVID patients.

In dogs the symptoms of infection include "sneezing, cough, hyaline rhinorrhea (Spanish term which could be translated as watery, perhaps profuse nasal discharge, diarrhea, vomiting, adynamia (weakness), and lack of appetite."

In the study 290 domestic animals were tested, 87.6% cats and 12.4% were dogs. Lab results showed a low but definite infection rate in both dogs and cats.

The report includes a list of the variations found in dogs and humans involved in the study which was conducted in northwestern Columbia.

Back in 2020 the journal Nature reported that dogs can be trained to smell out (so to speak) COVID infected people. 

https://www.icpcovid.com/sites/default/files/2021-03/Ep%20117-11%20Can%20dogs%20smell%20COVID_%20Here%E2%80%99s%20what%20the%20science%20says.pdf

Ellis EG. Thanks to sheltering in place, animal shelters are empty. [Accessed June 21, 2020]. https://www.wired.com/story/coronavirus-pet-adoption-boom. Published April 10, 2020.

The mental health of people forced to stay at home and actively avoid contact with other people will be a major problem that psychologists are already trying to deal with.

Perhaps the freelance writer (such as me) have a big advantage because writers are generally people who isolate themselves to have time and psychological energy to spend 8-10 hours a day writing, a notoriously solitary profession.


The CDC says little about pets other than that COVID can be transmitted both ways between pet and the pet's human.

https://www.cdc.gov/healthypets/covid-19/pets.html

They de-emphasize the risk but it is important to realize that new variants could be much more easily transmissible not just between humans but between humans and animals.

They do recommend isolating people with COVID both from other people in the household but also from any pets.

Saturday, September 4, 2021

Worrying new MU µ COVID variant found in 48 states but mostly FL is being carefully watched.

A scary new COVID variant known as the Mu (Greek letter µ) has emerged from Columbia and has been found in nearly 50 people resident in the UK. The official designation by the WHO, which designated it a “variant of interest” August 30, is B.1.621

Not much is known yet, including whether it spreads easily, or even if the current vaccines are effective against it.

Although there are only about 900 cases reported, it is found in 40 countries and virtually every U.S. state according to the GISAID tracking information.

https://www.gisaid.org/hcov19-variants/ (be patient, slow loading)

Mainly in France, Spain, and, of course, Florida.

An early test in Italy found that the Pfizer vaccine antibodies ARE effective against µ.

https://onlinelibrary.wiley.com/doi/10.1002/jmv.27247

HOWEVER, a study published in The Lancet shows otherwise because the spikes are different enough to evade current vaccines.

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00482-5/fulltext

µ causes high fevers and continuous coughs.








UK total distribution

Variant*Other names by which this variant may be known**LineageTotal confirmed (sequencing) and probable (genotyping) cases^New cases since last update (data up to 18 August)
AlphaVOC-20DEC-01B.1.1.7277,588-322
BetaVOC-20DEC-02B.1.3511,093+1
Delta†VOC-21APR-02B.1.617.2 AY.1 AY. 2535,387†+49,960
VOC-21FEB-02VOC-21FEB-02B.1.1.7 with E484K460
GammaVOC-21JAN-02P.1272+7
KappaVUI-21APR-01B.1.617.1494-1
VUI-21APR-03N/AB.1.617.3160
VUI-21FEB-01VUI-21FEB-01A.23.1 with E484K790
EtaVUI-21FEB-03B.1.525 (previously designated UK1188)497+2
VUI-21FEB-04VUI-21FEB-04B.1.1.318358+1
ZetaVUI-21JAN-01P.2600
ThetaVUI-21MAR-02P.3100
VUI-21MAY-01N/AAV.11850
VUI-21MAY-02N/AC.36.31530
LambdaVUI-21JUN-01C.3780
VUI-21JUL-01N/AB.1.62148+2

*Information pertaining to VUI-21MAR-01, B1.324.1 with E484K 

has been removed as this variant has been reclassified as provisionally extinct.

 

Wednesday, September 1, 2021

The Lancet reports true breakthrough infection rates - CDC has no good data.

British studies show breakthrough infection rates are extremely low, details follow:

The CDC doesn’t record the number of breakthrough infections, ONLY the ones which require hospitalizations, therefore the British study is definitive.

More than one million people who had one or two vaccination shots 


The mortality rate reported in the UK for those who are hospitalized with COVID-19 (any strain but mostly Delta in the UK) is nearly one-third.


Breakthrough infections are those which occur in people who have had at least one vaccination shot.


The UK measured the infections by self-reporting and testing so they include ALL people who catch COVID-19 EVEN IF THEY HAVE NO SYMPTOMS.


The results are great news because only 0.5% of those who had one of the two shots in the multi-shot vaccines developed COVID.


For those who were fully vaccinated the numbers were half as many, only 0.2%.


The following is a link to the original Lanced paper, it is extremely detailed and even more difficult to understand.


Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study - The Lancet Infectious Diseases